Is taking 'microdoses' of isotretinoin effective in treating acne?

Q: My teenager has severe acne and wants to try Accutane. I've heard some people are "microdosing" the drug to reduce side effects. Does it work?

Teenagers (and adults) with severe, painful, scarring acne can feel self-conscious, and because the condition is resistant to other treatments, dermatologists often prescribe isotretinoin , an oral medication commonly known by the brand name Accutane in the United States and in other Spanish-speaking countries as Roaccutane, Dercutane, Claravis, Neotrex, and Zenatane, among others.